And I still have hope it will be them and their shiny examples that will be a force to change the world. Some get infected and require removal. Garlic is toxic to dogs and cats. Vet mentioned new drug called Apoquel. This product is not for human use. However, using Apoquel combined with immunosuppressive agents, glucocorticoids and cyclosporine has not been declared safe yet. For most dogs, the appropriate dosage of Benadryl is perfectly safe. I thought doggie flu… turned her over to put a cool cloth on her belly and she was yellow (jaundice). Water under the bridge. I’m so glad you’re looking outside the box. Made up of Oclacitinib, a selective JAK-1 inhibitor, Apoquel provides instant relief … For her it is seasonal and pollens. Our pup will most likely die young from a complication from this drug. In case of accidental eye contact, flush immediately with water or saline for at least 15 minutes and then seek medical attention. I’ve read your Apoquel alternatives but not really getting much out of it. Took him to our local vet , they took x-rays and found 3 days of undigested food in his intestines. Two other dogs on APOQUEL were withdrawn from study due to suspected or confirmed malignant neoplasia and subsequently euthanized, including one dog that developed signs associated with a heart base mass after 21 days of APOQUEL administration, and one dog that developed a Grade III mast cell tumor after 60 days of APOQUEL administration. Since this was our first dog, we relied on whatever treatment our vet gave us. Based on a 2015 study, Apoquel as much as 0.4-0.6 mg/kg body weight could help to alleviate 40% feline atopic dermatitis symptoms. In dogs, oclacitinib maleate is rapidly and well absorbed following oral administration, with mean time to peak plasma concentrations (Tmax) of less than 1 hour. The dose of APOQUEL (oclacitinib maleate) tablets is 0.18 to 0.27 mg oclacitinib/lb (0.4 to 0.6 mg oclacitinib/kg) body weight, administered orally, twice daily for up to 14 days, and then administered once daily for maintenance therapy. The problem I have with homeopathy is I have tried 2 well known homeopathic vets with cats in the past and it did not result in many positive results, just ALOT of money spent so I am very cautious of that route now. PS: You absolutely may not have a vaccine waiver for any animal in the state of Washington. Adverse reactions reported (and percent of dogs affected) during Days 0-7 included diarrhea (2.3% APOQUEL, 0.9% placebo), vomiting (2.3% APOQUEL, 1.8% placebo), lethargy (1.8% APOQUEL, 1.4% placebo), anorexia (1.4% APOQUEL, 0% placebo), and polydipsia (1.4% APOQUEL, 0% placebo). Is Apoquel Safe for My Dog? If an animal is going to get ill on garlic, it’s Heinz Body Anemia, a red blood cell oxidation disorder, as I recall. She is on hydroxizine at the moment. The doctor is amazed at the fantastic turn around from the Apoquel. One of the reasons why veterinarians prefer apoquel over steroids and atopic is that apoquel has far fewer side effects. BOTTOM LINE: Antihistamines as an allergy medicine for dogs are generally very safe but not very effective. Just like humans, pneumonia is a serious medical condition for dogs. I have started home cooking a pork loin based meal to feed him once per day with Dr Becker/Mercola meal mix, Krill Oil, Ubiquinol, RX Zyme and Nutrigest added in. I’ve been to three homeopathic Vets and he just keeps getting worse. I was within 3 minute of an ER thankfully and they were waiting for me and they began administering Epinephrin .. She made it through. The estimated proportion of dogs with Treatment Success in Owner-assessed pruritus VAS score and in Veterinarian-assessed CADESI score was greater and significantly different for the APOQUEL group compared to the placebo group. I adopted my little white poodle mix Tori a year ago from the local shelter. The same “animal health” giant that makes Apoquel. Both of these interventions are sold as “prevention.”. During the 30-day study, there were no fatalities and no adverse reactions requiring hospital care. If I can soon find a new homeopathic vet to work with..there is great hope for this sweet loving guy! Well, I got a text from my sis this morning… her dog was fine yesterday afternoon.. began vomiting last night, bleeding from her rectum and has a 104 temp. This is chronic disease, and there’s no “one size fits all” here. Getting the dosage right is important … In Part One of this series, you saw a board certified veterinary dermatologist quoted, saying itchy dogs are caused by things like flea allergies and food allergies. Many of those “treatments” turn out to be the CAUSE. He has been allergy tested and is allergic to …. That just brings tons more dogs into the picture that can be affected. Instead, we see a state of chronic illness resulting from the vaccines. She has been for over 12 months, and we have worked to reduce the dosage to minimal amounts (currently half every other day). Apoquel is the brand name for the drug known as oclacitinib. Which remedy given when, at what potency, when to watch and wait, when to repeat, when to change remedies, all of that comes with professional training and experience. Most common side effects are vomiting and diarrhea. At that time we had no clue she was going to do that, she took him in the back room and said he had all the rest of his vaccines. well a LOT! Also the Distmeper vaccines, you can’t bring your pet to a therapy pool without those up to date. The Shou Wu tablets really seemed to help (from August 2015 – to late fall). Have a very Happy and Healthy New Year, Dr. Falconer. In some dogs, skin allergies are seasonal, so Apoquel side effects are less of an issue. What is comparable to apoquel for dogs? Wash hands immediately after handling the tablets. He is riddled with anxiety and misery. I have been conscious of heat and his diet(chinese medicine). Though people certainly try, and I wish it were possible, it’s simply too complex to think a supplement or diet or lifestyle change will cure such a state. *First, it is NOT a steroid (cortisone), antihistamine or cyclosporine. There is a responsibility and accountability on all sides to provide honest information based in fact, on solid ethical principles of business and scientific practice and with the foremost integrity to do no harm to the innocent domesticated pet who is at the mercy of benevolent pet owner who is only trying to give them the best love and life possible. Our experience suggests that it works great in around 50%, partially in around I had a holistic vet that gave me Chinese medicine for him, and it didn’t work. Lymphoid hyperplasia and chronic active inflammation was seen in lymph nodes draining feet affected with interdigital furunculosis. Oclacitinib has low protein binding with 66.3-69.7% bound in fortified canine plasma at nominal concentrations ranging from 10-1000 ng/mL. Usage of Apoquel causes side effects in many dogs. No drug can do that, if you haven’t realized that yet. I have a six year old golden/spaniel mix. They seems to help , but end up doing him more damage in the end. Seemed to work for a while with his coat returning to normal. But how safe is it to give your dog Apoquel? He didn’t look well. Necropsy revealed lesions consistent with sepsis secondary to immunosuppression. Veterinarians advise against using the drug while on continuous steroid therapy to be on the safer side. I don’t even let her walk on grass where chemical lawn spray signs are present. But I wish I had done it years ago. My sweet English Springer came to me at 8 weeks old with all her baby vaccines I took her for her Bortadella at I think it was around 12 – 15 weeks ? Gabapentin is best known under Pfizer’s brand name, Neurontin. I haven’t changed anything about her food (she was getting Steve’s Raw, rotating through all four protein sources); she hasn’t been exposed to any medicines, or chemicals. She has not stayed on it constantly but she has been on it for about 4 years off and on depending on symptoms. Odds are very high that, within a month prior, she had either: 1. You’ll find that on this page. Synthetic steroids duplicate the effect of naturally occuring steroids. Ugh, I’m at my witts end. When there’s a dangerous virus to be fought, sure, pour it on, turn up that inflammation, block it from reproducing, and kill that invader, for good and all. Also, vaccinations and allergies are only one of the many THEORIES on why allergies exist. So, I want to start by asking you to define “homeopathic” please. I knew it, I just knew it was too good to be true. Any suggestions I’m open for anything. An Apoquel container can either contain 20 or 100 tablets. ! But, the short answer is YES, help is out there. I am concerned that his previous long term intake of a salmon based kibble meal does not provide enough (or too much in the form of toxins) for my little man. My long coat German Shepherd, who was imported from Germany at 10 weeks old, and I took him home then, has been suffering since the day we got him. Nor the word “holistic.” These are two groups who don’t make things up in health outcomes. And to push a raw food diet is irresponsible. This guy sure does take the long way around the barn to get anywhere! I try to help with coconut oil, yogurt, apples… anything to get his stomach to settle and help him feel better. On your own, simply, at home? If you work with a homeopath, any allergies or sensitivies will go away too . This is fine for people with dairy allergies, Kay, as it’s a purified product: just these transfer factors, which are tiny immune molecules. Precautions for safe handling Keep tightly closed in a dry, cool and well-ventilated place. Six dogs were euthanized because of suspected malignant neoplasms: including thoracic metastatic, abdominal metastatic, splenic, frontal sinus, and intracranial neoplasms, and transitional cell carcinoma after 17, 120, 175, 49, 141, and 286 days of APOQUEL administration, respectively. Get off this drug if you’re giving it to your dog! This poor dog who already had a weak GI, and we had to be super careful with what we fed him, because he always seemed to have diarrhea. By definition, it means symptoms are somewhat better while treatment goes on, but nothing lasts. If you ever decide you want a trainer to get rid of the fear aggression, look at Sean O’Shea of The Good Dog Training & Rehabilitation. Of course, you’ll have to be very involved in the entire process. However, caution is advised if using liquid Benadryl as some artificial sweeteners, such as xylitol, are toxic to dogs. Apoquel is just recently known for its efficacy to cure canine atopic dermatitis (atopic dermatitis which occurs in dogs). Where in CA are you? Clinical observations that were considered likely to be related to oclacitinib maleate treatment included enlarged lymph nodes, interdigital furunculosis, cysts, and pododermatitis. zoetis One dog developed a low grade oral spindle cell sarcoma after 320 days of APOQUEL administration. Hi, he has had seasonal allergies for … Quite a lot, I would argue. Dogs that withdrew from the masked field study could enter an unmasked study where all dogs received APOQUEL. For more information, please visit www.APOQUEL.com References: 1. APOQUEL tablets contain 3.6 mg, 5.4 mg, or 16 mg of oclacitinib as oclacitinib maleate per tablet. They admit cancers that had been held in check (and therefore, often invisible so far) can take off and grow when this drug suppresses your dog’s immune system. One thing that I wonder about is whether she may have a weak immune system because she was born by cesarian section. PCV was at 24 when we arrived and by morning PCV was at 11. Death (including euthanasia) has been reported. Prior to that I had noticed an increase in scratching when she got beef. I asked my vet and she says no but I’ve noticed every time I give my 8 year old pit bull a pill, that same night she has really bad dreams. However Apoquel is recommended only for veterinary use. Its extremely unfortunate that this nonsense has such a high ranking for the search terms “apoquel side effects.” Homeopathy is absolute giberish, garbage, nonsense. Thanks for the great article. It takes hiring a veterinary homeopath who’s been trained in this amazing science. p.s. Thanks for the source. First with a GI problem , where he was thrashing on the floor and couldn’t get comfortable , 2nd day after we brought him home. My English vet colleague, Mr. Chris Day, MRCVS can help you get this youngster cured with homeopathy. I see no mention of intestinal permeability (“leaky gut”) here as a cause of allergic reaction … why? Like you it also won’t live forever. Tammy, have you considered trying CBD oil? We can, and MUST, demand transparency, ethics, and accountability on their part; yet we are responsible to work to become knowledgeable and accountable for our own care and decisions at the same time. Following IV and PO administration, the terminal t1/2 appeared similar with mean values of 3.5 (2.2, 4.7) and 4.1 (3.1, 5.2) hours, respectively. None of this should be surprising. 5 years ago he had a sudden neck lymphadenopathy that was initially diagnosed as lymphoma. A great place to start your search is my Recommended Resources page. It works by specifically targeting cytokines (a type of substance released by the immune system) to help stop itching and inflammation. A heartworm pill or 2. a vaccination. They will be healthier. All these questions and more will be asked by a good homeopath, as we seek to find the best remedy for your individual animal’s state of illness. In most cases, diarrhea, vomiting, anorexia, and lethargy spontaneously resolved with continued dosing. I was paying approximately $500–800 a month on vet bills from many vets – a dermatology specialist, urgent care, a vet in my area and my homeopathic vet who practices Chinese medicine and regular medicine depending on the situation. Any thoughts on the hydrolyzed protein diet? They didn’t cure it, as your experience makes clear. This is why I love and respect you so very much!!!! Thanks very much. The limping has eased somewhat. which if you read the literature, doesn’t occur often in dogs. Yes, it is safe to carry Apoquel while traveling onan airplane. However, these are not FDA approved drugs for the treatment of these problems in dogs. Unfortunately, it turned out to be anything but. Hence, Apoquel for cat has not been much studied yet. I did my research, found the drug to be very scary but felt no choice due to her suffering and began her on the drug. Use my Apoquel Alternatives Report to choose one who’ll help you reach cure by telephone appointments. In addition, each member is asked to list the percentage of their practice that is homeopathy. Just at a loss with where to go from here. Find a vet, near or far doesn’t matter, who. I don’t know how much mother’s milk she got, given that she was part of a litter of 11, and her dame may not have been able to feed the pups post surgery. They are on Rx food and my home cooking since one has an allergy to animal protein. I can’t give her raw food if she’s allergic to it, so how do I adjust? Hello do you know a holistic vet in Southern California ? Just be cautious with interfering with the immune system with something like Apoquel…I think in the years to come it will pan out how damaging this drug is. She has been minimally vaccinated as a puppy and has never received any boosters. TRUST YOURSELVES. At 2 she started with occasional (for no reason) diarrhea and vomiting. In many cases, it’s these things the pet has allergies to, and even with a perfect immune system, none of these are good for life. So he may be allergic to them as well. They have her on whatever life-support needed, testing her for cancer, etc…my poor sis is at her wits end…afraid she will lose her best friend! Thank You. Her skin became less flaky, and her hair grew back. Approved by FDA under NADA # 141-345 It has thoughtful articles and Tasty Tips that only go out to our members. The fact that you link vaccines to autism immediately discredits everything else on this website. Recently his panting and pacing have increased. Anytime I try to give him other sources he bites the fur completely off his back legs. There you’ll also find my free Apoquel Alternatives Report. Hi Daphne, Here in the province of Ontario, in Canada, it’s difficult to find a veterinarian who is solely involved in homeopathy as most of the few who exist blend both fields of homeopathy and traditional. For use in dogs only. 2. She invented a food sensitivity saliva-based test called Nutri-Scan. At an appropriate dose prescribed and … You can catch his very interesting finding on itchy dogs in my interview with him on this page. The mindset shift is this, Dolores: nothing in conventional medicine can cure what they’ve created here, called chronic disease. It was fabricated to begin with and it has been repeatedly proven that there is no link. They are safe for use in both dogs and cats. Adverse reactions reported (and percent of dogs affected) during Days 0-16 included diarrhea (4.6% APOQUEL, 3.4% placebo), vomiting (3.9% APOQUEL, 4.1% placebo), anorexia (2.6% APOQUEL, 0% placebo), new cutaneous or subcutaneous lump (2.6% APOQUEL, 2.7% placebo), and lethargy (2.0% APOQUEL, 1.4% placebo). The Vet had put her on Apoquel as an initial dose for 10 days tapering off. Keep away from heat, sparks and open flame. He’s been on a few other vet recommended remedies, such as sulphur, apis , phosphorus. After one week of treatment, the mean Veterinarian-assessed VAS dermatitis score for the dogs in the APOQUEL group was lower at 2.2 cm (improved from a baseline value of 6.2 cm) compared with the placebo group mean score of 4.9 cm (from a baseline value of 6.2 cm). Each tablet is scored and marked with AQ and either an S, M, or L that correspond to the different tablet strengths on both sides. This arena is unregulated and there are a lot of ‘snake oil’ salesman here as well. Because the trials are small compared to those of human therapeutics (in a best-case scenario, a few hundred animals), the FDA evaluates all of the data collected during the trial. Here’s what I see as true prevention, with some links to help you down that Natural Path.
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